|Donald Trump speaking after removing Anthony Scaramucci from his position|
Here are some of the senior scalps taken (so far) during the US President's turbulent short time in office:
Newly appointed White House communications chief Anthony Scaramucci
has been sacked after just 10 days in the West Wing.
Just days before, the former New York financier had let rip with an expletive-laden rant, calling a senior colleague a "paranoid schizophrenic" and threatening to "eliminate everyone" in his communications team.
The White House said the change had been made to give Mr Trump's new chief of staff, John F Kelly - who was sworn into office on the same day as Mr Scaramucci's removal - a "clean slate".
|Anthony Scaramucci has been removed from his position after just 10 days|
Chief of staff Reince Priebus was sacked after being made the subject of a foul-mouthed tirade by the newly appointed White House communications chief Anthony Scaramucci.
He accused Mr Priebus of being "a f****** paranoid schizophrenic" and of leaking information to the press.
Mr Priebus' 189-day tenure was the shortest in modern history for a White House chief of staff.
|Mr Priebus' tenure as White House chief of staff was the shortest in modern history|
Press secretary Sean Spicer quit after the appointment of Mr Scaramucci, warning over "too many cooks in the kitchen".
Mr Spicer, who had been standing in as communications director, had a stormy relationship with the press during his time in office, with his blustering, confrontational style being widely mocked.
Mr Trump said of him earlier this year: "He's doing a good job but he gets beat up."
|Sean Spicer had a stormy relationship with the press|
Mark Corallo, spokesman for the President's legal team, resigned amid reports of disagreements in dealing with the inquiry into claims of Russian meddling in last year's US election and possible collusion with the Trump campaign.
He was said to be frustrated over an alleged strategy by Mr Trump's lawyers to discredit or curb the investigation.
It is also reported Mr Trump's lead attorney Marc Kasowitz, who has represented the tycoon's interests for more than a decade, will also see his role reduced in relation to the Russia inquiry.
:: US government ethics chief Walter Shaub resigned after clashing with Mr Trump .
Tensions emerged before the Republican tycoon even took office, over his plan to hand control of his business empire to his two sons.
On stepping down, Mr Shaub, who served three presidents, said it had "become clear to me that we need improvements to the existing ethics program".
He later said he was concerned the US was "close to a laughing stock" when it came to holding other countries to high ethical standards.
White House communications director
Mike Dubke stepped down in May after just three months in the job.
It was reported the President had become frustrated with members of his team, pinning some of the blame for his administration's problems on the communications strategy.
FBI director James Comey learned he had been fired by Trump on the news.
Mr Trump said he had sacked Mr Comey for his handling of the investigation into Hillary Clinton's emails.
But Mr Comey testified that he believed he was fired to "change the way the Russia investigation was being conducted".
|James Comey learned he had been sacked as FBI chief on the news|
National security adviser Michael Flynn resigned after just 23 days in the job, over contacts he had with Russia before Mr Trump took office.
He was forced out after it emerged had discussed lifting US sanctions on Russia with the country's ambassador to Washington, and had then misled the US vice-president about the conversation.
|Michael Flynn was forced out as national security adviser after just 23 days|
Acting US attorney general Sally Yates was fired by the President after she defied him over his controversial travel ban.
She had ordered Justice Department lawyers not to enforce Mr Trump's immigration ban targeting seven Muslim-majority nations.
The then press secretary Sean Spicer said at the time that Ms Yates "has betrayed the Department of Justice by refusing to enforce a legal order designed to protect the citizens of the United States".
|Acting US attorney general Sally Yates defied the President over his travel ban|
:: Special prosecutor Robert Mueller has faced criticism from the President over his investigation into Russian interference in the US election and possible ties with the Trump campaign.
The White House has questioned the neutrality of Mr Mueller and sought to discredit him over his friendship with the sacked former FBI chief James Comey.
Such is the threat to Mr Mueller, Republican Senator Lindsey Graham is taking steps to block any move by the administration to sack the investigator.
Russia investigator Robert Mueller has faced criticism from the White house
:: The future of attorney general Jeff Sessions is looking decidedly unsure after the President described him as "beleaguered".
Mr Trump has said he is "very disappointed" in Mr Sessions and was "looking" at firing him.
He is angry about Mr Sessions removing himself from the Russia inquiry after failing to disclose a meeting with a Moscow official during his confirmation hearing.
However, Mr Graham has warned "there will be holy hell to pay" if Mr Sessions is fired.
|Mr Trump has said he is 'very disappointed' in US Attorney General Jeff Sessions|